新型冠状病毒引起的细胞因子风暴及其药物治疗

张竞文, 胡欣, 金鹏飞

中国药学杂志 ›› 2020, Vol. 55 ›› Issue (5) : 333-336.

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中国药学杂志 ›› 2020, Vol. 55 ›› Issue (5) : 333-336. DOI: 10.11669/cpj.2020.05.001
综述

新型冠状病毒引起的细胞因子风暴及其药物治疗

  • 张竞文1,2, 胡欣2, 金鹏飞2*
作者信息 +

Cytokine Storm Induced by SARS-CoV-2 and the Drug Therapy

  • ZHANG Jing-wen1,2, HU Xin2, JIN Peng-fei2*
Author information +
文章历史 +

摘要

2019年12月以来,新型冠状病毒(严重急性呼吸综合征冠状病毒2,SARS-CoV-2)感染在武汉暴发。近期不断有专家指出SARS-CoV-2感染者病情的突然加重可能和“炎症风暴”(细胞因子风暴)有关。但目前并无针对于此的特效药。笔者结合相关文献的检索和分析,对细胞因子风暴进行解读,对细胞因子风暴的药物治疗进行探索性综述,以期为临床治疗提供参考。

Abstract

Novel coronavirus 2019 (SARS-CoV-2) infection outbreak has occurred in Wuhan since December 2019.Cytokine storm (inflammatory factor storm)was suggested to be involved in the sudden deterioration of some SARS-CoV-2 infectors in the recent reports.However, no medicine was specific to the treatment of cytokine storm so far. This paper summarized the mechanism and potential therapeutic drugs of cytokine storm based on literature review and analysis, so as to provide references for the treatment of SARS-CoV-2.

关键词

新型冠状病毒 / 严重急性呼吸综合征冠状病毒2 / 炎症风暴 / 细胞因子风暴 / 药物治疗

Key words

novel coronavirus / SARS-CoV-2 / inflammatory factor storm / cytokine storm / drug therapy

引用本文

导出引用
张竞文, 胡欣, 金鹏飞. 新型冠状病毒引起的细胞因子风暴及其药物治疗[J]. 中国药学杂志, 2020, 55(5): 333-336 https://doi.org/10.11669/cpj.2020.05.001
ZHANG Jing-wen, HU Xin, JIN Peng-fei. Cytokine Storm Induced by SARS-CoV-2 and the Drug Therapy[J]. Chinese Pharmaceutical Journal, 2020, 55(5): 333-336 https://doi.org/10.11669/cpj.2020.05.001
中图分类号: R961   

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